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⭐ Featured VEO-linked integrated dataset • ENA deposition PRJEB87273 • Sewage metagenomics surveillance

European Urban Wastewater Virome Surveillance Dataset

VEO consortium partners (multi-city surveillance network)

This dataset (ENA accession PRJEB87273) contains integrated wastewater metagenomic sequencing data collected across multiple European surveillance sites. It includes microbial community profiles, antimicrobial resistance gene (ARG) detection, and metagenome-assembled genomes (MAGs), combined with spatial and temporal metadata. The dataset enables comparative analysis of pathogen circulation, resistome dynamics, and environmental drivers of infectious disease emergence in urban wastewater systems. It supports One Health surveillance approaches linking environmental, genomic, and epidemiological data streams.

🌊 Wastewater • 🧬 Metagenomics • 🦠 Pathogens • 🧫 AMR • 🌍 Europe-wide surveillance
Policy relevance: EU AMR surveillance • ECDC wastewater monitoring • Pandemic preparedness
🔗 ENA dataset (PRJEB87273) 📄 Associated publication (Nature Communications)
🧠 Key insight: Integrated wastewater metagenomics provides a continuous, population-level signal of pathogen circulation and antimicrobial resistance without clinical sampling bias.
Wastewater metagenomics surveillance overview

Conceptual overview of integrated sewage metagenomics surveillance pipeline (VEO framework).

VEO VEO Friedrich-Loeffler-Institute (FLI) Animal and Plant Health Agency (DEFRA) Eötvös Loránd University (ELTE) RIVM IFREMER AUTH AMC Institut Pasteur CSIC EPFL CBS University of Edinburgh University of Bologna University of Padova Uppsala University University of Helsinki University of Copenhagen UU European Commission DWHC Convergence WUR NIOO-KNAW Erasmus MC PDPC One Health Pact EMBL-EBI BY-COVID Pathogens Portal Universiteit Leiden

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