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⭐ Featured VEO-linked integrated dataset • Wastewater + Metagenomics + AMR + One Health surveillance

European Sewage Metagenomics Surveillance Resource (Five-city One Health dataset)

Koopmans & Aarestrup + VEO consortium partners

This integrated VEO-linked One Health dataset combines longitudinal sewage surveillance from five European cities with high-resolution metagenomic profiling. It includes microbial community composition, pathogen detection, antimicrobial resistance (AMR) gene abundance, and metagenome-assembled genomes (MAGs), all linked to spatial and temporal metadata. The dataset provides a unique framework for monitoring population-level microbial dynamics and antimicrobial resistance trends using wastewater as a proxy for human and environmental health.

🌊 Wastewater • 🧬 Metagenomics • 🦠 AMR • 📊 Epidemiology
Policy relevance: ECDC preparedness • One Health surveillance • AMR monitoring
📦 ENA sequencing dataset (PRJEB68319) 📊 Figshare dataset (metagenomic sewage resource) 🔧 GitHub database & analysis tools 📄 Associated publication (Oxford Database Journal)
🧠 Key insight: Wastewater metagenomics enables early detection of antimicrobial resistance and pathogen circulation before clinical reporting systems capture signals.
Sewage metagenomics overview

Conceptual workflow of sewage metagenomics surveillance across European cities.
© Oxford University Press (2025)

VEO VEO Friedrich-Loeffler-Institute (FLI) Animal and Plant Health Agency (DEFRA) Eötvös Loránd University (ELTE) RIVM IFREMER AUTH AMC Institut Pasteur CSIC EPFL CBS University of Edinburgh University of Bologna University of Padova Uppsala University University of Helsinki University of Copenhagen UU European Commission DWHC Convergence WUR NIOO-KNAW Erasmus MC PDPC One Health Pact EMBL-EBI BY-COVID Pathogens Portal Universiteit Leiden

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